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Allele : Tg(Ins2-TFRC/OVAL*)mT4Edp transgene insertion mT4, Ed Palmer
Primary Identifier  MGI:7858863 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ins2-TFRC/OVAL*)mT4Edp
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene consists of the rat insulin promoter (Ins2) driving the first 118 residues of the human transferrin receptor (TFRC), which includes the cytoplasmic tail and signal/anchor domain, fused to mature chicken ovalbumin (OVAL), residues 139-387 coding for (SIINFEKL), which was mutated by site-directed mutagenesis to (SIITFEKL) resulting in a membrane-bound form of ovalbumin.
  • mutations:
  • Insertion
  • synonyms:
  • RIP-mT4,
  • RIP-mT4
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1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

1 Driven By

2 Publication categories





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