| Primary Identifier | MGI:7853941 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Bcl11b |
| Transmission | Germline | Strain of Origin | (129 x C57BL/6)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A C to A substitution was introduced in exon 4 and a floxed neo cassette was inserted adjacent to exon 4 via homologous recombination. Cre mediated recombination removed the neo cassette. The change in exon 4 results in a missense mutation of aspargine to lysine at position 797 this is homologous to the N807K mutation in patients with inborn errors of immunity. |
