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Allele : Rr596<tm1.1Low> regulatory region 596; targeted mutation 1.1, Malcolm J Low
Primary Identifier  MGI:7853984 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Rr596
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Hypothalamic neuron-specific Pomc enhancers nPE1 and nPE2, located upstream of Pomc, were deleted (579 bp, 172 bp) and a loxP site flanked neomycin resistance gene cassette was inserted upstream of the nPE1 location. The neo cassette was removed through subsequent Cre-mediated recombination.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Pomc<deltanPE1.deltanPE2>,
  • Pomc<deltanPE1.deltanPE2>,
  • delta1delta2,
  • delta1delta2
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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