Primary Identifier | MGI:7858953 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Rr381 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Zbtb7b silencer, located upstream, was targeted with a dsODN template using TALEN technology (ZFN target sequences (capitalized) ACCGCTACCCTAACCcataaCTGGAAGGGGTTTAG), resulting in the mutation of three EGR (E6, E7, E9) and one NFAT (N5) binding sites. |