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DO Term : Lewy body dementia [DOID:12217] Disease Ontology

Namespace  disease_ontology Obsolete  false
description  A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies.
  • synonyms:
  • Dementia with Lewy bodies,
  • UMLS_CUI:C0752347,
  • ICD9CM:331.82,
  • NCI:C84826,
  • Diffuse Lewy body disease,
  • Lewy body disease,
  • Senile dementia of the Lewy body type,
  • MESH:D020961,
  • SNOMEDCT_US_2023_03_01:192808003,
  • OMIM:127750,
  • ICD10CM:G31.83,
  • GARD:3243,
  • 127750
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