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MP Term : increased circulating gamma-glutamyl transferase level [MP:0031114] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  elevated blood level of the enzyme that catalyzes the transfer of gamma-glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate); GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione as well as drug and xenobiotic detoxification; GGT is present in many organs throughout the body, with the highest concentrations found in liver, and elevated in the blood in most diseases that cause damage to the liver or bile ducts
  • synonyms:
  • increased circulating GGT level,
  • increased circulating gamma-GT level,
  • increased circulating gamma-glutamyl transpeptidase level
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents