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MP Term : increased circulating angiotensin II level [MP:0031232] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  increased concentration in the blood of angiotensin II, a vasoactive octapeptide produced by the action of angiotensin-converting enzyme on angiotensin I; it acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone
  • synonyms:
  • elevated circulating angiotensin II level,
  • increased serum angiotensin II level,
  • increased plasma angiotensin II level
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents