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GO Term : ESC/E(Z) complex [GO:0035098] Gene Ontology

Namespace

cellular_component

Obsolete

false

description

A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.

synonyms:
polycomb repressive complex 2,
Extra Sex Combs/Enhancer of Zeste complex,
PRC2 complex

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents

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