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GO Term : tumor necrosis factor production [GO:0032640] Gene Ontology

Namespace  biological_process Obsolete  false
description  The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
  • synonyms:
  • TNF-alpha biosynthesis,
  • GO:0042533,
  • TNF alpha biosynthesis,
  • Tnfa production,
  • tumor necrosis factor-alpha production,
  • TNF-alpha biosynthetic process,
  • GO:1990774,
  • TNF biosynthetic process,
  • TNF-alpha production,
  • TNF production,
  • tumor necrosis factor formation,
  • TNF biosynthesis,
  • tumor necrosis factor biosynthetic process,
  • cachectin production,
  • tumor necrosis factor anabolism,
  • tumor necrosis factor synthesis,
  • tumor necrosis factor biosynthesis,
  • tumor necrosis factor secretion
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