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GO Term : SCF ubiquitin ligase complex [GO:0019005] Gene Ontology

Namespace  cellular_component Obsolete  false
description  A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
  • synonyms:
  • Cul1-RING ubiquitin ligase complex,
  • CRL1 complex,
  • CDL1 complex,
  • SCF complex,
  • SCF complex substrate recognition subunit,
  • cullin-RING ligase 1,
  • Skp1/Cul1/F-box protein complex
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Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents