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GO Term : methylenetetrahydrofolate reductase (NAD(P)H) activity [GO:0004489] Gene Ontology

Namespace

molecular_function

Obsolete

false

description

Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.

synonyms:
5,10-methylenetetrahydrofolic acid reductase activity,
N(5),N(10)-methylenetetrahydrofolate reductase activity,
5,10-CH(2)-H(4)folate reductase activity,
5-methyltetrahydrofolate:NAD oxidoreductase activity,
MTHFR activity,
methylenetetrahydrofolate reductase activity,
5,10-methylenetetrahydrofolate reductase activity,
5,10-methylenetetrahydrofolate reductase (NADPH) activity,
5,10-methylenetetrahydrofolate reductase (FADH) activity,
N5,N10-methylenetetrahydrofolate reductase activity,
5,10-methylenetetrahydrofolate reductase (FADH(2)) activity,
methylenetetrahydrofolate reductase (NADPH2),
5,10-methylenetetrahydrofolate reductase (FADH2) activity,
5-methyltetrahydrofolate:(acceptor) oxidoreductase activity,
MetF,
5-methyltetrahydrofolate:NADP(+) oxidoreductase activity,
methylenetetrahydrofolic acid reductase activity,
methylenetetrahydrofolate reductase (NADPH(2)) activity,
5,10-methylenetetrahydropteroylglutamate reductase activity,
5-methyltetrahydrofolate:NAD(+) oxidoreductase activity,
5,10-CH2-H4folate reductase activity,
5-methyltetrahydrofolate:NADP+ oxidoreductase activity,
N(5,10)-methylenetetrahydrofolate reductase activity,
5-methyltetrahydrofolate:NAD+ oxidoreductase activity,
methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity,
methylenetetrahydrofolate reductase [NAD(P)H],
5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity,
GO:0008702,
methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity,
N5,10-methylenetetrahydrofolate reductase activity

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents

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