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Publication : Mitochondrial malate dehydrogenase (Mor-1) in the mouse: linkage to chromosome 5 markers.

First Author  Womack JE Year  1975
Journal  Biochem Genet Volume  13
Issue  9-10 Pages  519-25
PubMed ID  1203052 Mgi Jnum  J:5602
Mgi Id  MGI:54079 Doi  10.1007/BF00484911
Citation  Womack JE, et al. (1975) Mitochondrial malate dehydrogenase (Mor-1) in the mouse: linkage to chromosome 5 markers. Biochem Genet 13(9-10):519-25
abstractText  Malate dehydrogenase is present in most mammalian tissues in both supernatant and mitochondrial forms. Although genetic variation for the supernatant form has not been observed in the mouse, electrophoretic variants caused by alleles at the mitochondrial locus (Mor-1) have been previously described. We have located this locus 11.0 +/- 2.9 cM from the beta-glucuronidase structural gene, Gus, on chromosome 5. The gene order is Hm-Pgm-1-rd-bf-Gus-Mor-1. Thus Mor-1 is presently the most distal marker on chromosome 5. Three different nuclear loci for mitochondrial enzymes (Mod-2, Got-2, and Mor-1) have now been mapped in the mouse, all on different chromosomes.
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