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Publication : A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3.

First Author  Lundin LG Year  1987
Journal  Biochem Genet Volume  25
Issue  7-8 Pages  603-10
PubMed ID  3447593 Mgi Jnum  J:9140
Mgi Id  MGI:57603 Doi  10.1007/BF00554361
Citation  Lundin LG (1987) A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3. Biochem Genet 25(7-8):603-10
abstractText  A gene (Bmn) with a major effect on beta-mannosidase activity in kidney and liver of the house mouse was revealed by assay with the synthetic substrate p-nitrophenyl-beta-D-mannoside. Activity is low in DBA/2J and CSB mice and high in C57BL/6J mice. By the use of the BXD series of recombinant inbred strains and by crosses between C57BL and CSB, it was possible to map the gene to the distal part of chromosome 3 by demonstration of linkage to a gene for cadmium resistance, cdm, as well as to the Adh-3 locus.
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