First Author | Lundin LG | Year | 1987 |
Journal | Biochem Genet | Volume | 25 |
Issue | 7-8 | Pages | 603-10 |
PubMed ID | 3447593 | Mgi Jnum | J:9140 |
Mgi Id | MGI:57603 | Doi | 10.1007/BF00554361 |
Citation | Lundin LG (1987) A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3. Biochem Genet 25(7-8):603-10 |
abstractText | A gene (Bmn) with a major effect on beta-mannosidase activity in kidney and liver of the house mouse was revealed by assay with the synthetic substrate p-nitrophenyl-beta-D-mannoside. Activity is low in DBA/2J and CSB mice and high in C57BL/6J mice. By the use of the BXD series of recombinant inbred strains and by crosses between C57BL and CSB, it was possible to map the gene to the distal part of chromosome 3 by demonstration of linkage to a gene for cadmium resistance, cdm, as well as to the Adh-3 locus. |