| First Author | Chamberlain JS | Year | 1987 |
| Journal | Somat Cell Mol Genet | Volume | 13 |
| Issue | 6 | Pages | 671-8 |
| PubMed ID | 2890215 | Mgi Jnum | J:8903 |
| Mgi Id | MGI:57368 | Doi | 10.1007/BF01534487 |
| Citation | Chamberlain JS, et al. (1987) Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome. Somat Cell Mol Genet 13(6):671-8 |
| abstractText | The murine locus corresponding to the human Duchenne/Becker muscular dystrophy (DMD) gene has been regionally mapped on the mouse X chromosome by hybridizing DNA from interspecies mouse crosses with a cDNA clone for the mouse Dmd gene. The results demonstrate that the relative organization of genes on the murine and human X chromosomes is more divergent than has previously been postulated. Furthermore, the mouse Dmd gene maps to a similar region of the X chromosome as does the mouse muscular dystrophy mutation mdx, providing further evidence that the mdx mutant may be a murine equivalent of human DMD. However, Southern analysis of portions of the mouse Dmd gene has not yet revealed any differences between mdx and wild-type mice. |
