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Publication : Additional evidence for the close linkage of amy-1 and amy-2 in the mouse.

First Author  Bloor JH Year  1980
Journal  J Hered Volume  71
Issue  6 Pages  449-51
PubMed ID  6163812 Mgi Jnum  J:6487
Mgi Id  MGI:54963 Doi  10.1093/oxfordjournals.jhered.a109413
Citation  Bloor JH, et al. (1980) Additional evidence for the close linkage of amy-1 and amy-2 in the mouse. J Hered 71(6):449-51
abstractText  The enzyme amylase is produced in large quantities in two mammalian tissues, the pancreas and the parotid salivary gland. A substantial body of biochemical and genetic evidence is consistent with the existence of distinct genes encoding salivary and pancreatic amylases, but testcrosses in mice have indicated that the two putative loci must be very closely linked. We have studied crosses between two pairs of inbred mice that differ with respect to electrophoretic mobility of salivary and pancreatic amylases. Among 343 potentially recombinant chromosomes examined, no recombinants were found. Our data sets an upper limit of 0.87 cM (P = 0.95) for the distance between the salivary and pancreatic loci.
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