| First Author | Ferreira GC | Year | 1995 |
| Journal | Biochem Biophys Res Commun | Volume | 214 |
| Issue | 3 | Pages | 875-8 |
| PubMed ID | 7575558 | Mgi Jnum | J:28927 |
| Mgi Id | MGI:76464 | Doi | 10.1006/bbrc.1995.2368 |
| Citation | Ferreira GC (1995) Ferrochelatase binds the iron-responsive element present in the erythroid 5-aminolevulinate synthase mRNA. Biochem Biophys Res Commun 214(3):875-8 |
| abstractText | Ferrochelatase, the terminal enzyme of the heme biosynthetic pathway, binds an iron-responsive element (IRE) present in the 5'untranslated region of the mRNA for erythroid 5-aminolevulinate synthase, the first enzyme of the heme biosynthetic pathway. This IRE-binding activity of ferrochelatase may play a critical role in the regulation of heme biosynthesis in differentiating erythrocytes. |
