First Author | Schmidt CJ | Year | 1994 |
Journal | J Neurosci Res | Volume | 38 |
Issue | 2 | Pages | 182-7 |
PubMed ID | 8078103 | Mgi Jnum | J:18498 |
Mgi Id | MGI:66779 | Doi | 10.1002/jnr.490380208 |
Citation | Schmidt CJ, et al. (1994) G(O), a guanine nucleotide binding protein, is expressed during neurite extension in the embryonic mouse. J Neurosci Res 38(2):182-7 |
abstractText | The developmental pattern of expression of the G protein alpha o subunit and GAP43 were compared by immunohistochemical staining of mouse embryos. Staining for alpha o and GAP43 was identical and detected throughout the developing nervous system, and the antigens first appeared in neurons at the beginning of neuronal differentiation. GAP43 and alpha o were not detected in regions containing only neuroblasts. These observations suggest that alpha o and GAP43 may not be required for the decision to pass from neuroblast to differentiated neuron, but may play a role in signal transduction during early neuronal development. |