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Publication : Electrophoretic variation for x-chromosome-linked phosphoglycerate kinase (pgk-1) in the mouse.

First Author  Nielsen JT Year  1977
Journal  Genetics Volume  87
Issue  2 Pages  319-25
PubMed ID  17248765 Mgi Jnum  J:4489
Mgi Id  MGI:52978 Doi  10.1093/genetics/87.2.319
Citation  Nielsen JT, et al. (1977) Electrophoretic Variation for X-Chromosome-Linked Phosphoglycerate Kinase (Pgk-1) in the Mouse. Genetics 87(2):319-325
abstractText  Electrophoretic variation for X-chromosome-linked phosphoglycerate kinase (PGK-1) has been found as a polymorphism in feral mice in Denmark. Males from feral sampling or from a variety of genetic crosses have only a single-banded phenotype of the variant PGK-1A type or of the PGK-1B type commonly found among inbred mice. By contrast, three phenotypes were observed among females; two homozygous single-banded types and a heterozygous double-banded type. The X-chromosome linkage of the Pgk-1 locus was determined from the mode of inheritance in F(1) and backcross generations and confirmed by the linkage of Pgk-1 and the X-linked markers Hq, Ta and Mo. Pgk-1 showed 29/122 recombinations with Hq, 5/185 with Ta and 0/108 recombinants with Mo. Based on these recombination data, a gene order of Hq-Ta-Pgk-1-Mo is suggested.
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