| First Author | Smith SM | Year | 2017 |
| Journal | Front Mol Biosci | Volume | 4 |
| Pages | 72 | PubMed ID | 29184887 |
| Mgi Jnum | J:320128 | Mgi Id | MGI:6869967 |
| Doi | 10.3389/fmolb.2017.00072 | Citation | Smith SM, et al. (2017) Weak Molecular Interactions in Clathrin-Mediated Endocytosis. Front Mol Biosci 4:72 |
| abstractText | Clathrin-mediated endocytosis is a process by which specific molecules are internalized from the cell periphery for delivery to early endosomes. The key stages in this step-wise process, from the starting point of cargo recognition, to the later stage of assembly of the clathrin coat, are dependent on weak interactions between a large network of proteins. This review discusses the structural and functional data that have improved our knowledge and understanding of the main weak molecular interactions implicated in clathrin-mediated endocytosis, with a particular focus on the two key proteins: AP2 and clathrin. |
