First Author | Shime H | Year | 2002 |
Journal | Infect Immun | Volume | 70 |
Issue | 11 | Pages | 6460-3 |
PubMed ID | 12379728 | Mgi Jnum | J:221562 |
Mgi Id | MGI:5640953 | Doi | 10.1128/IAI.70.11.6460-6463.2002 |
Citation | Shime H, et al. (2002) Association of Pasteurella multocida toxin with vimentin. Infect Immun 70(11):6460-3 |
abstractText | To help understand the molecular mechanisms of Pasteurella multocida toxin (PMT) action, we searched for a cellular protein interacting with PMT. The ligand overlay assay revealed a 60-kDa cellular protein that binds to a region from the 840th to 985th amino acids of the toxin. This protein was identified as vimentin by peptide mass fingerprinting. The N-terminal head domain of vimentin was further found to be responsible for the binding to the toxin. |