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Publication : Molecular cloning and characterization of a novel phospholemman-like protein from rat hippocampus.

First Author  Yamaguchi F Year  2001
Journal  Brain Res Mol Brain Res Volume  86
Issue  1-2 Pages  189-92
PubMed ID  11165386 Mgi Jnum  J:67206
Mgi Id  MGI:1930057 Doi  10.1016/s0169-328x(00)00213-8
Citation  Yamaguchi F, et al. (2001) Molecular cloning and characterization of a novel phospholemman-like protein from rat hippocampus. Brain Res Mol Brain Res 86(1-2):189-92
abstractText  A cDNA encoding a putative ion channel protein was isolated from a rat hippocampus library. This gene, termed phosphohippolin (Php), contains 318 bp open reading frame encoding a single transmembrane protein with a 5' signal peptide region. The deduced amino acid sequence shares 48.1% homology with phospholemman (Plm). Expression sequence tag database (dEST) search identified a mouse (AA521976) and human (AA209241) Php gene homologues. The tissue distribution studies of Php mRNA showed its abundant expression in rat brain and kidney, and in the brain, high expression was observed in hippocampus and cerebellum.
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