First Author | Hollemann T | Year | 2000 |
Journal | Dev Genes Evol | Volume | 210 |
Issue | 11 | Pages | 579-81 |
PubMed ID | 11180810 | Mgi Jnum | J:65844 |
Mgi Id | MGI:1927374 | Doi | 10.1007/s004270050350 |
Citation | Hollemann T, et al. (2000) Xnkx-2.1: a homeobox gene expressed during early forebrain, lung and thyroid development in Xenopus laevis. Dev Genes Evol 210(11):579-81 |
abstractText | Nkx-2.1 is a member of the vertebrate Nkx family of homeobox genes; it was originally identified as a tissue-specific regulator of thyroglobulin and thyroperoxidase gene transcription. Here we report on the embryonic expression of Xnkx-2.1, which is expressed in the presumptive forebrain from early neurulation onwards. In tadpole stage embryos Xnkx-2.1 transcripts are primarily detected in ventral forebrain, lung buds and thyroid anlage. Therefore, Xnkx-2.1 may be part of the genetic network that controls the early development of these organs. |