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Publication : Estrogen receptor- and aromatase-deficient mice provide insight into the roles of estrogen within the ovary and uterus.

First Author  Rosenfeld CS Year  2001
Journal  Mol Reprod Dev Volume  59
Issue  3 Pages  336-46
PubMed ID  11424220 Mgi Jnum  J:69885
Mgi Id  MGI:2135706 Doi  10.1002/mrd.1039
Citation  Rosenfeld CS, et al. (2001) Estrogen receptor- and aromatase-deficient mice provide insight into the roles of estrogen within the ovary and uterus. Mol Reprod Dev 59(3):336-46
abstractText  Estrogen receptor (ER)- (alpha, beta, and both alpha and beta) and aromatase (Ar) knockout (KO) mice have been created to assess the biological effects of estrogens. This review article discusses the ovarian and uterine phenotypes of these mice. The data obtained have confirmed some older inferences about how the steroid acts, but have also revealed some unexpected aspects of estrogen action. Mol. Reprod. Dev. 59:336-346, 2001. Copyright 2001 Wiley-Liss, Inc.
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