| First Author | Ratti A | Year | 2001 |
| Journal | Cytogenet Cell Genet | Volume | 92 |
| Issue | 3-4 | Pages | 279-82 |
| PubMed ID | 11435701 | Mgi Jnum | J:70472 |
| Mgi Id | MGI:2137436 | Doi | 10.1159/000056916 |
| Citation | Ratti A, et al. (2001) Cloning and molecular characterization of three ubiquitin fusion degradation 1 (Ufd1) ortholog genes from Xenopus laevis, Gallus gallus and Drosophila melanogaster. Cytogenet Cell Genet 92(3-4):279-82 |
| abstractText | The yeast ubiquitin fusion degradation 1 (Ufd1) protein is involved in a degradation pathway for ubiquitin fused products. The human ortholog gene (UFD1-like, UFD1L) is deleted in patients affected by the DiGeorge/velocardiofacial syndromes. We report the cloning of UFD1L orthologs from Drosophila melanogaster (dufd1l), Xenopus laevis and Gallus gallus. The 1,125-bp Drosophila cDNA encodes a protein of 316 amino acids, showing 60% identity with the human and murine proteins. The identity to the G. gallus, X. laevis, C. elegans and S. cerevisiae proteins is 95%, 83%, 32%, and 36%, respectively. Northern expression data in Drosophila indicate that dufd1l is expressed through embryonic, larval and pupal development, as well as in the adult fly. Copyright 2001 S. Karger AG, Basel. |
