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Publication : Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat.

First Author  Yamada K Year  2001
Journal  Cytogenet Cell Genet Volume  94
Issue  1-2 Pages  39-42
PubMed ID  11701952 Mgi Jnum  J:73180
Mgi Id  MGI:2154659 Doi  10.1159/000048780
Citation  Yamada K, et al. (2001) Comparative FISH mapping of Gab1 and Gab2 genes in human, mouse and rat. Cytogenet Cell Genet 94(1-2):39-42
abstractText  Gab1 and Gab2 are members of the Gab family which act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. We determined chromosome locations of the two genes in human, mouse and rat by fluorescence in situ hybridization. The Gab1 gene was localized to chromosome 4q31.1 in human, 8C3 in mouse and 19q11.1--> q11.2 in rat, and the Gab2 gene was located on chromosome 11q13.4-->q13.5 in human, 7E2 in mouse and 1q33.2-->q33.3 in rat. All human, mouse and rat Gab1 and Gab2 genes were localized to chromosome regions where conserved homology has been identified among the three species.
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