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Publication : NHEJ deficiency and disease.

First Author  Pierce AJ Year  2001
Journal  Mol Cell Volume  8
Issue  6 Pages  1160-1
PubMed ID  11885597 Mgi Jnum  J:75234
Mgi Id  MGI:2176117 Doi  10.1016/s1097-2765(01)00424-5
Citation  Pierce AJ, et al. (2001) NHEJ deficiency and disease. Mol Cell 8(6):1160-1
abstractText  In mouse and human, diseases associated with deficiency of DNA ligase IV, a protein involved in DNA double-strand break repair, have been identified. Manifestation of some of these disease phenotypes, namely tumorigenesis, may require additional checkpoint deficiencies.
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