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Publication : The multidrug resistance protein family.

First Author  Borst P Year  1999
Journal  Biochim Biophys Acta Volume  1461
Issue  2 Pages  347-57
PubMed ID  10581366 Mgi Jnum  J:58883
Mgi Id  MGI:1350539 Doi  10.1016/s0005-2736(99)00167-4
Citation  Borst P, et al. (1999) The multidrug resistance protein family. Biochim Biophys Acta 1461(2):347-57
abstractText  The human multidrug resistance protein (MRP) family contains at least six members: MRP1, the godfather of the family and well known as the multidrug resistance protein, and five homologs, called MRP2-6. In this review, we summarize what is known about the protein structure, the expression in tissues, the routing in cells, the physiological functions, the substrate specificity, and the role in multidrug resistance of the individual members of the MRP family.
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