First Author | Giraldo P | Year | 1999 |
Journal | Genet Anal | Volume | 15 |
Issue | 3-5 | Pages | 175-8 |
PubMed ID | 10596759 | Mgi Jnum | J:59815 |
Mgi Id | MGI:1352185 | Doi | 10.1016/s1050-3862(99)00023-6 |
Citation | Giraldo P, et al. (1999) The use of yeast artificial chromosomes in transgenic animals: expression studies of the tyrosinase gene in transgenic mice. Genet Anal 15(3-5):175-8 |
abstractText | Variegation and inherited somatic mosaicism has been observed in transgenic mice carrying yeast artificial chromosomes (YACs) in which a DNAse I hypersensitive site (HS) located -12 kb upstream of the mouse tyrosinase gene had been deleted. At present, we are generating new transgenic animals with minor deletions of the HS. |