| First Author | Sala CF | Year | 2000 |
| Journal | Biochem Biophys Res Commun | Volume | 273 |
| Issue | 1 | Pages | 27-34 |
| PubMed ID | 10873558 | Mgi Jnum | J:62887 |
| Mgi Id | MGI:1860016 | Doi | 10.1006/bbrc.2000.2882 |
| Citation | Sala CF, et al. (2000) Identification, gene structure, and expression of human frizzled-3 (FZD3). Biochem Biophys Res Commun 273(1):27-34 |
| abstractText | We report the identification, genomic structure, chromosomal localization, and expression analysis of human frizzled-3 (FZD3), a 7-transmembrane receptor belonging to the frizzled family. The cDNA obtained from adult human brain shows 91% identity at the nucleotide level and 98% at the amino acid level to mouse frizzled-3 (fzd3). The FZD3 locus is located on chromosome 8p21, spans 48 Kb and its coding sequence is distributed in 6 exons intercalated by 5 introns. FZD3 is expressed in all analyzed human tissues, with quantitatively higher expression in the CNS and in urogenital structures. Copyright 2000 Academic Press. |
