First Author | Gambardella L | Year | 2000 |
Journal | Mech Dev | Volume | 96 |
Issue | 2 | Pages | 215-8 |
PubMed ID | 10960786 | Mgi Jnum | J:64340 |
Mgi Id | MGI:1889117 | Doi | 10.1016/s0925-4773(00)00398-1 |
Citation | Gambardella L, et al. (2000) Pattern of expression of the transcription factor krox-20 in mouse hair follicle. Mech Dev 96(2):215-8 |
abstractText | We examined the pattern of expression in hair follicles of the transcription factor gene Krox-20. During embryogenesis, Krox-20 is first expressed in the upper portion of the hair bud, then in the hair canal, in the sebaceous glands and in the outer root sheath. In the mature follicles, Krox-20, like Shh and TGFbetaRII, is also expressed in a sub-population of matrix keratinocytes located in a ring-like fashion in vibrissal follicles and clustered on one side of the papilla in pelage follicles. This polarized pattern rotates around the papilla as a result of sequential gene expression by individual groups of matrix cells. This peculiar pattern is not linked to follicle angling. |