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Publication : Pattern of expression of the transcription factor Krox-20 in mouse hair follicle.

First Author  Gambardella L Year  2000
Journal  Mech Dev Volume  96
Issue  2 Pages  215-8
PubMed ID  10960786 Mgi Jnum  J:64340
Mgi Id  MGI:1889117 Doi  10.1016/s0925-4773(00)00398-1
Citation  Gambardella L, et al. (2000) Pattern of expression of the transcription factor krox-20 in mouse hair follicle. Mech Dev 96(2):215-8
abstractText  We examined the pattern of expression in hair follicles of the transcription factor gene Krox-20. During embryogenesis, Krox-20 is first expressed in the upper portion of the hair bud, then in the hair canal, in the sebaceous glands and in the outer root sheath. In the mature follicles, Krox-20, like Shh and TGFbetaRII, is also expressed in a sub-population of matrix keratinocytes located in a ring-like fashion in vibrissal follicles and clustered on one side of the papilla in pelage follicles. This polarized pattern rotates around the papilla as a result of sequential gene expression by individual groups of matrix cells. This peculiar pattern is not linked to follicle angling.
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