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Publication : Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material.

First Author  Chattopadhyay SK Year  1975
Journal  Proc Natl Acad Sci U S A Volume  72
Issue  3 Pages  906-10
PubMed ID  1055389 Mgi Jnum  J:5536
Mgi Id  MGI:54014 Doi  10.1073/pnas.72.3.906
Citation  Chattopadhyay SK, et al. (1975) Definitive evidence that the murine C-type virus inducing locus Akv-1 is viral genetic material. Proc Natl Acad Sci U S A 72(3):906-10
abstractText  DNA of the AKR mouse contains a set of murine leukemia virus sequences that are not present in DNA of the NIH Swiss mouse. NIH mice partially congenic for the AKR murine-leukemia-virus-inducing locus Akv-1 contain this set of sequences, and, in a three-point cross segregating for Akv-1 on an NIH background, the sequences segregated with Akv-1. It is concluded that the Akv-1 locus contains viral sequences.
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