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Publication : Chromosomal location of soluble glutamic-pyruvic transaminase-1 (Gpt-1) in the mouse.

First Author  Eicher EM Year  1977
Journal  Biochem Genet Volume  15
Issue  1-2 Pages  1-8
PubMed ID  849243 Mgi Jnum  J:5796
Mgi Id  MGI:54273 Doi  10.1007/BF00484544
Citation  Eicher EM, et al. (1977) Chromosomal location of soluble glutamic-pyruvic transaminase-1 (Gpt-1) in the mouse. Biochem Genet 15(1-2):1-8
abstractText  Three alleles at the Gpt-1 (glutamic-pyruvic transaminase-1) locus in the mouse, as identified by electrophoresis on cellulose acetate, and their distribution among inbred mouse strains and wild stocks are described. The Gpt-1 locus was shown to control the soluble form of the enzyme. Three-point linkage analysis established th location of Gpt-1 on chromosome 15 between uw and bt. In addition, a new staining procedure is described that allows the visualization of GPT activity on gels by the deposition of formazan. This is an improvement over previous methods that produced bands of nonfluorescence against a fluorescent background.
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