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Publication : Chromosomal assignment of the mouse kappa light chain genes.

First Author  Swan D Year  1979
Journal  Proc Natl Acad Sci U S A Volume  76
Issue  6 Pages  2735-9
PubMed ID  111241 Mgi Jnum  J:6181
Mgi Id  MGI:54658 Doi  10.1073/pnas.76.6.2735
Citation  Swan D, et al. (1979) Chromosomal assignment of the mouse kappa light chain genes. Proc Natl Acad Sci U S A 76(6):2735-9
abstractText  Mouse-hamster somatic cell hybrids containing a variable number of mouse chromosomes have been used in experiments to determine which mouse chromosome carries the immunoglobulin kappa light chain genes. It has been shown by nucleic acid hybridization that the kappa constant gene and the genes for at least one variable region subgroup are on mouse chromosome 6. This somatic cell genetic mapping procedure appears to be general and can be applied to any expressed or silent gene for which an appropriate nucleic acid probe exists.
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