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Publication : Genetic variation in alkaline phosphatase of the house mouse (Mus musculus) with emphasis on a manganese-requiring isozyme.

First Author  Wilcox FH Year  1979
Journal  Biochem Genet Volume  17
Issue  11-12 Pages  1093-107
PubMed ID  540002 Mgi Jnum  J:6286
Mgi Id  MGI:54763 Doi  10.1007/BF00504347
Citation  Wilcox FH, et al. (1979) Genetic variation in alkaline phosphatase of the house mouse (Mus musculus) with emphasis on a manganese-requiring isozyme. Biochem Genet 17(11-12):1093-107
abstractText  Genetic variation among inbred strains is described for electrophoretic migration of alkaline phosphatase from intestine, kidney, blood plasma, and three isozymes of liver. A manganese-requiring isozyme of liver and kidney unaffected by neuraminidase is described, and the locus controlling variation in this isozyme is designated Akp-1. Data from recombinant inbred strains place the locus on chromosome 1 at a distance of 3.6 +/- 2.9 cM from the M1s locus on the side distal to the centromere. Test-cross data show the following gene order and recombination percentages: Dip-1 19.0 +/- 3.8% Lp 7.4 +/- 2.2% Akp-1.
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