| First Author | Gorin MB | Year | 1980 |
| Journal | Proc Natl Acad Sci U S A | Volume | 77 |
| Issue | 3 | Pages | 1351-5 |
| PubMed ID | 6154931 | Mgi Jnum | J:31564 |
| Mgi Id | MGI:79146 | Doi | 10.1073/pnas.77.3.1351 |
| Citation | Gorin MB, et al. (1980) Structure of the alpha-fetoprotein gene in the mouse. Proc Natl Acad Sci U S A 77(3):1351-5 |
| abstractText | The mouse alpha-fetoprotein mRNA is the product of a single-copy gene whose mRNA coding sequences are represented discontinuously in the genome. Several EcoRI genomic fragments which contain portions of the alpha-fetoprotein gene have been cloned using the EK2 vector lambda gt WES . lambda B. In addition, a mouse genomic library has been screened to obtain a 15.75-kilobase segment of DNA that includes more than 85% of the alpha-fetoprotein coding sequence. Analyses by restriction endonuclease mapping and electron microscopy showed that the mRNA sequence is interrupted by at least 11 intervening sequences which occupy 90% of the cloned DNA. |
