| First Author | Takahashi N | Year | 1980 |
| Journal | Gene | Volume | 11 |
| Issue | 1-2 | Pages | 117-27 |
| PubMed ID | 7439686 | Mgi Jnum | J:6427 |
| Mgi Id | MGI:54903 | Doi | 10.1016/0378-1119(80)90092-x |
| Citation | Takahashi N, et al. (1980) Nucleotide sequences of class-switch recombination region of the mouse immunoglobulin gamma 2b-chain gene. Gene 11(1-2):117-27 |
| abstractText | We have cloned a rearranged gamma 2b-chain gene from mouse myeloma MOPC141. Nucleotide-sequence determination demonstrated that the rearranged gamma 2b-chain gene was formed by a recombination between the region flanking the 5'-ends of the embryonic mu-chain gene and that of the gamma 2b-chain genes. Nucleotide sequences similar to the one located adjacent to the recombination site were found in other parts of the region flanking the 5'-end of the mu-chain-gene, as well as in the region flanking the 5'-end of the gamma 1-chain gene. The common sequence (GGTANNAAAGNAC) shares extensive homology with the sequence proximal to the insertion site of the bacterial insertion element IS2. |
