First Author | Goding JW | Year | 1981 |
Journal | J Immunol | Volume | 126 |
Issue | 4 | Pages | 1644-6 |
PubMed ID | 6162896 | Mgi Jnum | J:6476 |
Mgi Id | MGI:54952 | Doi | 10.4049/jimmunol.126.4.1644 |
Citation | Goding JW (1981) Evidence for linkage of murine beta 2-microglobulin to H-3 and Ly-4. J Immunol 126(4):1644-6 |
abstractText | Murine beta 2-microglobulin exists in 2 electrophoretically distinct forms; C57BL/6 mice possess the basic allele whereas BALB/c, CBA, AKR, and NZB possess the acidic allele. Mice heterozygous for beta 2-microglobulin express both alleles. Analysis of recombinant inbred mice suggests linkage of beta 2-microglobulin to H-2 or H-3. B10.C (28NX) mice (which possess the H-3c allele of BALB/c on a C57BL/10 background) possess the acid allele. Taken together, these results are consistent with the beta 2-microglobulin gene lying on chromosome 2, and being linked to H-3 and Ly-4. |