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Publication : Evidence for linkage of murine beta 2-microglobulin to H-3 and Ly-4.

First Author  Goding JW Year  1981
Journal  J Immunol Volume  126
Issue  4 Pages  1644-6
PubMed ID  6162896 Mgi Jnum  J:6476
Mgi Id  MGI:54952 Doi  10.4049/jimmunol.126.4.1644
Citation  Goding JW (1981) Evidence for linkage of murine beta 2-microglobulin to H-3 and Ly-4. J Immunol 126(4):1644-6
abstractText  Murine beta 2-microglobulin exists in 2 electrophoretically distinct forms; C57BL/6 mice possess the basic allele whereas BALB/c, CBA, AKR, and NZB possess the acidic allele. Mice heterozygous for beta 2-microglobulin express both alleles. Analysis of recombinant inbred mice suggests linkage of beta 2-microglobulin to H-2 or H-3. B10.C (28NX) mice (which possess the H-3c allele of BALB/c on a C57BL/10 background) possess the acid allele. Taken together, these results are consistent with the beta 2-microglobulin gene lying on chromosome 2, and being linked to H-3 and Ly-4.
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