| First Author | Gasser DL | Year | 1981 |
| Journal | Proc Natl Acad Sci U S A | Volume | 78 |
| Issue | 5 | Pages | 3147-50 |
| PubMed ID | 6942422 | Mgi Jnum | J:6551 |
| Mgi Id | MGI:55026 | Doi | 10.1073/pnas.78.5.3147 |
| Citation | Gasser DL, et al. (1981) Genes in mice that affect susceptibility to cortisone-induced cleft palate are closely linked to Ir genes on chromosomes 2 and 17. Proc Natl Acad Sci U S A 78(5):3147-50 |
| abstractText | Inbred and congeneic strains of mice have been examined for susceptibility to cortisone-induced cleft palate, and the role of genes linked to H-2 on chromosome 17 has been confirmed. Increasing degrees of susceptibility were associated with the H-2d, H-2b, H-2k, and H-2a haplotypes, respectively, with H-2q and H-2s also being associated with fairly high levels of susceptibility. Evidence was obtained that suggests that one gene maps within the B region of H-2, and that a second H-2 linked gene which acts by complementation maps to the right of E. Another gene affecting this trait is closely linked to the H-3 and Ir-2 loci on the second chromosome. |
