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Publication : Characterization of a highly repetitive family of DNA sequences in the mouse.

First Author  Fanning TG Year  1982
Journal  Nucleic Acids Res Volume  10
Issue  16 Pages  5003-13
PubMed ID  6290999 Mgi Jnum  J:15764
Mgi Id  MGI:63877 Doi  10.1093/nar/10.16.5003
Citation  Fanning TG (1982) Characterization of a highly repetitive family of DNA sequences in the mouse. Nucleic Acids Res 10(16):5003-13
abstractText  A large proportion (0.5-1%) of total mouse DNA is cleaved by Bam HI into fragments whose size is about 500 base pairs. A cloned member of this repetitive family of DNA sequences (BAM5 family) was sequenced by the dideoxy chain termination procedure and shown to contain 507 base pairs. The sequence exhibited no unusual or remarkable features. Repetitive sequences complementary to the cloned BAM5 fragment were found in rat DNA, but not in feline or human DNA. Restriction mapping suggested that many BAM5 sequences were components of much larger repetitive DNAs which were scattered throughout the mouse genome. The BAM5 sequences within the larger repetitive DNAs did not appear to be arranged tandemly or as members of scrambled tandem repeats. RNA homologous to the cloned BAM5 sequence was detected in cultured mouse cells, but not in cultured rat cells.
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