| First Author | Flaherty L | Year | 1982 |
| Journal | Immunogenetics | Volume | 16 |
| Issue | 4 | Pages | 329-37 |
| PubMed ID | 7173999 | Mgi Jnum | J:6916 |
| Mgi Id | MGI:55388 | Doi | 10.1007/BF00372304 |
| Citation | Flaherty L, et al. (1982) Syngeneic tumor immunizations produce Qa antibodies. Discovery of a new Qa antigen, Qa-6. Immunogenetics 16(4):329-37 |
| abstractText | BALB/cBy (Qa-2-) mice injected with the syngeneic tumor, ORA I-a (Qa-2+), produced antibodies to Qa-2 and a newly discovered antigen, Qa-6. Specific antisera against Qa-6, in the presence of complement, lyses approximately 40% of lymph-node lymphocytes and splenocytes. Strain distribution analyses indicate that Qa-6 is specified by a gene within the TL subregion of the major histocompatibility complex. Thus, Qa-6 is the third member of the Qa/TL subset of cell surface antigens which is anomalously expressed on certain tumor cells. This finding suggests that the Qa and TL molecules may have a unique, functional role on the cell surface. |
