First Author | Chen IS | Year | 1983 |
Journal | J Virol | Volume | 45 |
Issue | 1 | Pages | 104-13 |
PubMed ID | 6296425 | Mgi Jnum | J:6954 |
Mgi Id | MGI:55425 | Doi | 10.1128/jvi.45.1.104-113.1983 |
Citation | Chen IS, et al. (1983) Structure and expression of c-rel, the cellular homolog to the oncogene of reticuloendotheliosis virus strain T. J Virol 45(1):104-13 |
abstractText | The cellular homolog of the onc sequences in the avian retrovirus reticuloendotheliosis virus strain T (v-rel) was studied by molecular cloning and nucleic acid hybridization. In contrast to v-rel sequences, which are 1.4 kilobase pairs long, the cellular homolog, c-rel, from line 15B chickens is at least 25 kilobase pairs long, with multiple apparent introns. A 4.0-kilobase polyadenylic acid-containing RNA transcript is the primary species of c-rel RNA present in uninfected chicken cells. Sequences at the 3' end of this c-rel RNA are not present in v-rel. |