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Publication : Evidence for a new lymphocyte-stimulating determinant (Lsd) detected by alloreactive T cell lines.

First Author  Opalka B Year  1983
Journal  Eur J Immunol Volume  13
Issue  1 Pages  24-30
PubMed ID  6601005 Mgi Jnum  J:7007
Mgi Id  MGI:55478 Doi  10.1002/eji.1830130107
Citation  Opalka B, et al. (1983) Evidence for a new lymphocyte-stimulating determinant (Lsd) detected by alloreactive T cell lines. Eur J Immunol 13(1):24-30
abstractText  Three alloreactive T cell clones are described which reveal a new lymphocyte-stimulating determinant (Lsd) controlled by a gene on chromosome 1 of the mouse but different from and possibly centromeric to Mls. Two clones were originally isolated as anti-H-2b-specific and showed and retained cross-reactivity to Lsd (clone OD3, BALB/c anti-C57BL/6; clone KB37, B10.BR anti-C57BL/10). The third clone (BD7, C57BL/6 anti-CBA/J) was probably originally directed against Lsd. So far, Lsd is only characterized by stimulation of T cell proliferation, and its physiological function is not yet known.
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