First Author | Wood C | Year | 1983 |
Journal | Proc Natl Acad Sci U S A | Volume | 80 |
Issue | 10 | Pages | 3030-4 |
PubMed ID | 6407007 | Mgi Jnum | J:7079 |
Mgi Id | MGI:55550 | Doi | 10.1073/pnas.80.10.3030 |
Citation | Wood C, et al. (1983) Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism. Proc Natl Acad Sci U S A 80(10):3030-4 |
abstractText | We have mapped 12 diversity (D) gene segments of mouse Ig heavy chains between 80 and 1 kilobases 5' to the four joining (JH) gene segments by molecular analysis of DNA clones isolated from recombinant phage and cosmid libraries. All identified D and JH segments are in the same 5'-3' orientation. The significance of these findings with respect to the joining mechanism for Ig gene segments is discussed. |