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Publication : Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.

First Author  Honey NK Year  1984
Journal  Somat Cell Mol Genet Volume  10
Issue  4 Pages  377-83
PubMed ID  6589791 Mgi Jnum  J:7529
Mgi Id  MGI:55999 Doi  10.1007/BF01535633
Citation  Honey NK, et al. (1984) Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse. Somat Cell Mol Genet 10(4):377-83
abstractText  The mouse genes for the serine proteases trypsin (Try-1), chymotrypsin B (Ctrb), and elastase (Ela-1) were chromosomally assigned using Southern blot hybridization of mouse X Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb, and Ela-1 was correlated with the segregation of mouse chromosomes. Try-1 is located on chromosome 6, Ctrb is on chromosome 8, and Ela-1 is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes.
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