First Author | Honey NK | Year | 1984 |
Journal | Somat Cell Mol Genet | Volume | 10 |
Issue | 4 | Pages | 377-83 |
PubMed ID | 6589791 | Mgi Jnum | J:7529 |
Mgi Id | MGI:55999 | Doi | 10.1007/BF01535633 |
Citation | Honey NK, et al. (1984) Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse. Somat Cell Mol Genet 10(4):377-83 |
abstractText | The mouse genes for the serine proteases trypsin (Try-1), chymotrypsin B (Ctrb), and elastase (Ela-1) were chromosomally assigned using Southern blot hybridization of mouse X Chinese hamster cell hybrid DNA. cDNA probes for the three genes were hybridized to cell hybrid DNA cleaved with BamHI or HindIII and the segregation of Try-1, Ctrb, and Ela-1 was correlated with the segregation of mouse chromosomes. Try-1 is located on chromosome 6, Ctrb is on chromosome 8, and Ela-1 is on chromosome 15. The three genes fall into three syntenic groups that are conserved in the mouse and human genomes. |