| First Author | Elston RC | Year | 1984 |
| Journal | Genetics | Volume | 108 |
| Issue | 3 | Pages | 733-44 |
| PubMed ID | 6500262 | Mgi Jnum | J:45314 |
| Mgi Id | MGI:1195012 | Doi | 10.1093/genetics/108.3.733 |
| Citation | Elston RC (1984) The genetic analysis of quantitative trait differences between two homozygous lines. Genetics 108(3):733-44 |
| abstractText | Previous maximum likelihood methods to analyze quantitative data on two inbred parental strains, their F1 and backcross generations are extended in three directions: (1) a method is suggested to transform the data to better satisfy the assumptions of normality and homoscedasticity; (2) the likelihoods are modified to allow for litter correlations and heteroscedasticity and (3) allowance is made for the incorporation of F2 data. The problem of making a choice among a set of simple genetic hypotheses is further discussed. |
