| First Author | Sukhatme VP | Year | 1985 |
| Journal | J Exp Med | Volume | 161 |
| Issue | 2 | Pages | 429-34 |
| PubMed ID | 3919142 | Mgi Jnum | J:7744 |
| Mgi Id | MGI:56213 | Doi | 10.1084/jem.161.2.429 |
| Citation | Sukhatme VP, et al. (1985) Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2. J Exp Med 161(2):429-34 |
| abstractText | We have mapped the gene encoding the T cell differentiation antigen Leu-2/T8 to human chromosome 2 by hybridization of a Leu-2/T8 complementary DNA clone to DNA from a panel of mouse-human cell hybrids. In situ hybridization further localizes the gene to the 2p1 region in close proximity to the Ig kappa light chain gene. The Leu-2/T8 gene translocates with C kappa to chromosome 8 in a Burkitt lymphoma line carrying a t(2;8) translocation. These data support the hypothesis that Leu-2/T8 is the human homologue of the mouse Lyt-2,3 antigen. |
