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Publication : Mapping cell surface antigens on mouse pre-B cell lines.

First Author  McKearn JP Year  1985
Journal  Eur J Immunol Volume  15
Issue  3 Pages  295-8
PubMed ID  2579825 Mgi Jnum  J:33455
Mgi Id  MGI:80935 Doi  10.1002/eji.1830150316
Citation  McKearn JP, et al. (1985) Mapping cell surface antigens on mouse pre-B cell lines. Eur J Immunol 15(3):295-8
abstractText  Characterization of cell surface molecules expressed by B cell precursors has been hampered by the inability to routinely assay such cells from freshly explanted normal lymphoid tissues. However, a large number of transformed pre-B cell clones have been isolated which presumably include those precursors recently entering the B cell lineage (obtained from fetal liver and more rarely from adult bone marrow) and extending to those clones which are poised to become surface Ig-positive B cells. In this report, we have quantitated expression of 10 different cell surface molecules, 5 of which bear special interest as B cell differentiation antigens, among a large panel of pre-B cell clones.
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