First Author | McKearn JP | Year | 1985 |
Journal | Eur J Immunol | Volume | 15 |
Issue | 3 | Pages | 295-8 |
PubMed ID | 2579825 | Mgi Jnum | J:33455 |
Mgi Id | MGI:80935 | Doi | 10.1002/eji.1830150316 |
Citation | McKearn JP, et al. (1985) Mapping cell surface antigens on mouse pre-B cell lines. Eur J Immunol 15(3):295-8 |
abstractText | Characterization of cell surface molecules expressed by B cell precursors has been hampered by the inability to routinely assay such cells from freshly explanted normal lymphoid tissues. However, a large number of transformed pre-B cell clones have been isolated which presumably include those precursors recently entering the B cell lineage (obtained from fetal liver and more rarely from adult bone marrow) and extending to those clones which are poised to become surface Ig-positive B cells. In this report, we have quantitated expression of 10 different cell surface molecules, 5 of which bear special interest as B cell differentiation antigens, among a large panel of pre-B cell clones. |