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Publication : Genetic differences between two substrains of NZB mice.

First Author  Oikawa T Year  1985
Journal  J Immunogenet Volume  12
Issue  1 Pages  71-3
PubMed ID  3862713 Mgi Jnum  J:8033
Mgi Id  MGI:56502 Doi  10.1111/j.1744-313x.1985.tb00831.x
Citation  Oikawa T, et al. (1985) Genetic differences between two substrains of NZB mice. J Immunogenet 12(1):71-3
abstractText  We have compared the NZB/B1NJ (/NJ) and NZB/B1Pt (/Pt) mouse substrains with respect to a number of immunological and biochemical polymorphisms. In agreement with earlier findings by other workers, we detected histocompatibility antigen difference(s) between the two substrains. Serological analysis indicated that /NJ and /Pt expressed the same allotypes of H-2, Thy-1 and Lyt-1 antigens, while they differed for the Lyt-2 antigen. Amongst 15 biochemical polymorphisms, which we assayed, /NJ and /Pt differed for four, namely Pep-3, Mup-1, Gpd-1 and Hbb. In addition, the two NZB substrains differed for the Hc marker (haemolytic complement).
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