| First Author | Read AP | Year | 1986 |
| Journal | Hum Genet | Volume | 73 |
| Issue | 3 | Pages | 267-70 |
| PubMed ID | 3015770 | Mgi Jnum | J:8359 |
| Mgi Id | MGI:56826 | Doi | 10.1007/BF00401242 |
| Citation | Read AP, et al. (1986) Mapping of human X-linked hypophosphataemic rickets by multilocus linkage analysis. Hum Genet 73(3):267-70 |
| abstractText | Eleven families with X-linked dominant hypophosphataemic rickets (HPDR) have been typed for a series of X chromosome markers. Linkage with probe 99.6 (DXS41) was demonstrated with a peak lod score of 4.82 at 10% recombination. Multilocus linkage analysis showed that HPDR maps distal to 99.6; this probe has previously been located at Xp22.31-p21.3 by in situ hybridisation. In the mouse hypophosphataemia (Hyp) maps to the distal part of the X chromosome; our location in man is consistent with a scheme which relates the mouse and human X chromosomes by two rearrangements. No marker has yet been found which shows no recombination with HPDR. |
